Maternal Floor Infarction Definition

A tendency to recur in subsequent pregnancies has been reported.

Maternal floor infarction definition.

Maternal floor infarction mfi and its related disorder massive perivillous fibrin deposit mpfd is an uncommon placental abnormality of unknown pathogenesis. Large placental infarcts are associated with vascular abnormalities e g. May be accompanied by massive perivillous fibrin deposition. 1 benirschke suggested that lack of fissuring of the decidua basalis in a term placenta was abnormal and he coined the term maternal floor.

Small placental infarcts especially at the edge of the placental disc are considered to be normal at term. A pathologic entity characterised by deposition of fibrinoid material in the maternal surface and intervillous spaces of the placenta and which is associated with significant perinatal morbidity and mortality including stillbirth recurrent pregnancy loss premature delivery intrauterine growth restriction and neurodevelopmental impairment. It is characterized by the deposition of fibrin in the decidua basalis and intervillous space where enveloped villi become avascular and sclerotic. Instead it refers to extensive gross thickening of the maternal surface of the placenta with fibrin or matrix often in the context of fetal growth retardation or death.

The condition is associated with adverse perinatal outcome including spontaneous abortion preterm delivery fetal growth restriction stillbirth and long term neurologic impairment as well as recurrent risk in subsequent pregnancies. Hypertrophic decidual vasculopathy as seen in hypertension. Maternal floor infarction is associated with intrauterine growth retardation and fetal demise. A placental infarction results from the interruption of blood supply to a part of the placenta causing its cells to die.

Maternal floor infarction mfi was originally described by benirschke in 1961 as a passing comment accompanied by a figure in an article focused on the examination of the placenta. Massive deposition of intervillous fibrin that entrap the villi of the basal plate extending to a thickness of at least 3 mm. Very large infarcts lead to placental insufficiency and may result in fetal death. It frequently recurs in successive pregnancies.

Massive perivillous fibrin deposition mpfd and maternal floor infarction mfi are related placental lesions often associated with fetal death and fetal growth restriction. Seen in 0 09 0 5 of placentas. Associated with recurrent abortions stillbirth fetal growth restriction or neurologic impairment. 1 he described a lesion on the maternal surface of the placenta in which the thin layer of the decidua basalis is covered by small amounts of calcium and fibrin.

In this study of mfi and the related placental disorder massive perivillous fibrin deposition mfd semiquantitative histologic criteria for these diagnoses are defined and rates of iugr and recurrence are assessed.