In this study of mfi and the related placental disorder massive perivillous fibrin deposition mfd semiquantitative histologic criteria for these diagnoses are defined and rates of iugr and recurrence are assessed.
Maternal floor infarction placenta.
Maternal floor infarction then logically should refer to obstruction of blood flow of the arterial entrance to the intervillous space causing necrosis of the overlying placenta.
Low maternal blood volume may contribute to the low blood flow because maternal hemoglobin values were often abnormally high in gravidas in whom floor infarcts developed.
The term infarction is a misnomer because true placental infarcts result from arterial occlusion and ischemic necrosis of the villi.
Maternal floor infarction of the placenta is characterized by gross placental abnormalities and histologic evidence of x cell proliferation.
Maternal floor infarction of the placenta is a relatively rare disorder that leads to sudden iufd2 incidence.
Maternal floor infarction frequently recurs in successive pregnancies rate 39 2 and there is evidence that it develops rapidly.
The disease is characterized by extensive fibrin deposition in the intervillous spaces.
The pathophysiology of the lesion remains unclear.
Damage to the decidua basalis by ischemia or infection may initiate many floor infarcts.
Maternal floor infarction mfi is an uncommon placental disease associated with recurrent third trimester fetal loss and intrauterine growth retardation iugr usually severe.
It is also known as massive perivillous fibrin deposition.
The enveloped villi become atrophic and avascular.
To compare cranial ultrasound studies and neurodevelopmental outcome of preterm infants affected by maternal floor infarction mfi of the placenta to gestational age matched controls.
Maternal floor infarction mfi is a poorly understood placental lesion reportedly associated with intrauterine growth restriction iugr and recurrence.
Maternal floor infarction abbreviated mfi is a pathology of the placenta.
Definition general massive deposition of intervillous fibrin that entrap the villi of the basal plate extending to a thickness of at least 3 mm may be accompanied by massive perivillous fibrin deposition associated with recurrent abortions stillbirth fetal growth restriction or neurologic impairment.
Maternal floor infarction occurred in 3 11 of these 28 cases.
In the 6 cases without placental histologic findings available mfi seemed unlikely because all 6 had normal outcomes.
Of the 28 cases with placental histologic find ings available extensive subchorionic fibrin deposition had been reported in 14 cases 50.
Atheroma in the decidual arteries foci of decidual necrosis and histologic evidence of low uteroplacental blood flow were more frequent in patients with floor infarcts.
